Clinical Spotlight: Vaginal Weights vs. Tolterodine for Overactive Bladder

A 2016 randomized clinical trial published in the European Journal of Obstetrics & Gynecology and Reproductive Biology explored the effectiveness of pelvic floor muscle training (PFMT) using vaginal weights versus Tolterodine, a commonly prescribed anticholinergic, for treating overactive bladder (OAB) in women.


Study Design

The study assessed changes in:
  • Lower urinary tract symptoms (LUTS)
  • Sexual function
  • Quality of life (QOL)
Validated tools included:
  • UDI-6
  • IIQ-7
  • OAB-V8
  • Wagoner’s Questionnaire for QOL
Urodynamic testing and 24-hour pad tests were performed before and after the intervention.

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Treatment Groups

✔️ Vaginal Weight Group:
Participants used one of four progressively heavier cones for 10 minutes, twice daily, while standing or doing light activity. Once they could maintain a weight beyond 10 minutes, they advanced to the next level.

✔️  Tolterodine Group:
Participants took 4 mg of Tolterodine daily. Both groups had check-ins at 4 and 8 weeks to monitor adherence and side effects.

Outcomes

  • Both groups showed a ~68% reduction in pad weight at 8 weeks.
  • The vaginal weight group had a significant increase in pelvic floor strength and improvements across all outcome measures—including QOL.
  • The medication group improved in all areas except the Wagoner QOL score.
  • Detrusor overactivity resolved in 8 patients using vaginal weights vs. just 2 in the medication group.
No adverse effects were reported in either group.


Clinical Implication

This study supports vaginal weights as a safe, effective, and conservative treatment for OAB—particularly for symptoms like urgency and frequency. The 10-minute, twice-daily protocol, though more intensive than typical recommendations, was well tolerated and highly effective.


1. Yucay T., Dokmeci F, Cetinkaya S. A prospective randomized trial comparing the use of tolterodine or weighted vaginal cones in women with overactive bladder syndrome. European Journal of Obstetrics & Gynecology and Reproductive Biology. (2016)197: 91-97. 

2. O’Sullivan R, Karantanis E, Stevermuer TL, Allen W, Moore KH. Definition of mild, moderate and severe incontinence on the 24-hour pad test. BJOG
2004;111(8):859–62.

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Regain your confidence in just 15 minutes a day! Tighter and stronger vaginal muscles offer improved bladder control, enhanced intimacy, easier labor and faster childbirth recovery.

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